PEER-REVIEWED ARTICLE
An injectable hyaluronic acid-Polydeoxyribonucleotides (HA-PDRN) crosslinked hydrogel as a dermal filler
Guo jiahong · Fang wei · Wang feifeiEuropean Polymer Journal 2024, 219(), 113395DOI 10.1016/j.eurpolymj.2024.113395 ↗
The supplied index reports: HA and PDRN were covalently linked to form a hydrogel, which was assessed for viscoelasticity, hydration, degradation, injectability and biocompatibility, and compared with HA crosslinked hydrogel. In mouse experiments, volume maintenance beyond 24 weeks and changes in inflammatory and collagen-related findings were recorded.
The HA-PDRN crosslinked hydrogel maintained volume beyond 24 weeks after injection in mice.Volume maintenance after injection in mice
Changes related to inflammation and collagen synthesis were observed after injection.Tissue response in mice
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Complete publication and citation identifiers.
- DOI
- 10.1016/j.eurpolymj.2024.113395
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- Published
- 2024-10-16
- Volume / Issue / Article
- 219 / / 113395
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