PEER-REVIEWED ARTICLE
Exploration of Ultrasound-Enhanced Transdermal Delivery Efficiency and Anti-Inflammatory Effect of Rutin
Yue Q · He B · Guo Z · Zhang N · Zhang M · Zhang YPharmaceuticals (Basel, Switzerland) 2025, 18(4), 464DOI 10.3390/ph18040464 ↗
The supplied index reports diffusion experiments comparing intradermal retention of rutin under different ultrasound parameters in porcine and nude-mouse skin. Under the recorded conditions, specific parameters yielded intradermal retention ratios of 1.8-fold and 2.63-fold versus no ultrasound, and ultrasound-assisted treatment showed faster barrier recovery in a tape-stripping mouse model.
Under the recorded conditions, specific ultrasound parameters increased the intradermal retention ratio of rutin to 1.8- and 2.63-fold versus no ultrasound, from different skin models.Diffusion experiments on different skin models
Ultrasound-assisted rutin treatment showed faster recovery than spontaneous recovery, with barrier function restoration observed on day 4.Tape-stripping mouse model (n=8 per group)
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Complete publication and citation identifiers.
- DOI
- 10.3390/ph18040464
- ISSN
- Published
- 2025-03-26
- Volume / Issue / Article
- 18 / 4 / 464
- Publisher
- Keywords