PEER-REVIEWED ARTICLE

The extract of buddleja officinalis maxim. alleviates UVB-induced oxidative damage via the NRF2 pathway in HaCaT cells

Xu Zhu · Zhongyi Chen · Bin Deng · Chunhao Yang · Fengkun XiaoPharmaceutical biology 2025, 63(1), 567-581DOI 10.1080/13880209.2025.2540348 ↗

The supplied index reports an in vitro study: Buddleja officinalis extract was subjected to compositional analysis and free-radical-scavenging assays, and its effects were assessed in UVB-irradiated HaCaT cells. The extract partially reduced oxidative damage markers and altered the expression of NRF2, HO-1 and NQO1.

In UVB-irradiated HaCaT cells, the extract partially reduced oxidative damage markers.In vitro cell model; index summary
The extract altered the expression of NRF2, HO-1 and NQO1.Pathway expression assay; index summary