Three-Dimensional Bioprinted Skin Microrelief and Its Role in Skin Aging

The supplied index reports that the study used DLP 3D printing to create samples with age-related skin microrelief and performed wrinkle formation simulations using a modified Voronoi algorithm. Experimental and numerical results indicated that microrelief affected the elastic modulus of the samples and that epidermal mechanical changes played an important role in wrinkle formation; the authors proposed the hypothesis that microrelief may help skin adapt to age-related mechanical changes.