PEER-REVIEWED ARTICLE

UPLC-QTOF-MS profiling combined with GNPS and evaluation of antioxidant activity in aqueous extracts from Metapanax delavayi leaves

Rui Xu · Yonglei Yuan · Liping Qu · Feifei WangApplied Food Research 2026, 6(1), 101887DOI 10.1016/j.afres.2026.101887 ↗

The supplied index reports: This study compared three water-based extraction methods for Metapanax delavayi leaves using UPLC-QTOF-MS/MS and GNPS molecular networking for compound identification and annotation. Under the tested conditions, subcritical water extraction performed favourably in yield, compositional diversity and antioxidant activity.

A total of 136 compounds were identified or annotatedAnalysis of aqueous extracts from Metapanax delavayi leaves by UPLC-QTOF-MS/MS and GNPS molecular networking; 12 key constituents were further confirmed against reference standards
Under the tested conditions, subcritical water extraction performed favourably in yield, compositional diversity and antioxidant activityComparison of three water-based extraction methods (including subcritical water extraction) for Metapanax delavayi leaves