痤疮中的皮肤免疫过程综述

输入索引记载：本综述梳理了痤疮发病中的皮肤免疫过程，涉及皮脂、微生物、毛囊角化和局部炎症因素，以及先天与适应性免疫细胞的响应。作者指出，疾病不同阶段的免疫时空模式尚未被充分阐明，并讨论了单细胞与空间RNA测序等方法的潜在价值。

The supplied index reports: This review examines skin immune processes in acne, covering sebum, microorganisms, follicular keratinization, local inflammation, and innate and adaptive immune cell responses. The authors note that the precise spatiotemporal immune patterns at different disease stages remain poorly characterized, and discuss the potential of single-cell and spatial RNA sequencing approaches.