非剥脱点阵激光联合日常精华护理的随机半脸研究

输入索引记载，一项单中心双盲随机半脸试验，37名受试者入组，33名35-49岁女性完成，全脸接受一次非剥脱点阵激光后，将一种多成分精华和空白配方随机用于左右半脸，每日两次共28天。仪器检测与医生评价显示，测试侧部分皱纹及鼻唇沟指标出现变化，无严重不良事件，1例轻度水肿被认为与激光相关且3天内自行缓解。

The supplied index reports a single-centre, double-blind, randomised split-face trial: 37 enrolled, 33 women aged 35–49 completed; after one full-face nonablative fractional laser treatment, a multi-ingredient serum and a blank formulation were applied to opposite sides twice daily for 28 days. Instrumental and physician assessments recorded changes in several wrinkle and nasolabial fold parameters; no serious adverse events occurred, and one mild oedema attributed to laser resolved within three days.