PEER-REVIEWED ARTICLE · 同行评议论文
可注射HA-PDRN交联水凝胶的材料性能与动物评价
An injectable hyaluronic acid-Polydeoxyribonucleotides (HA-PDRN) crosslinked hydrogel as a dermal filler输入索引记载：研究通过透明质酸的羧基与PDRN的氨基形成共价连接，制备交联水凝胶，评估黏弹性、水合、降解、注射性与生物相容性，并与透明质酸交联水凝胶比较。小鼠体内实验中，研究记录到超过24周的体积维持，以及炎症与胶原合成相关变化。
护肤研发启示
输入索引记载：该研究为皮肤相关生物材料提供了结构、性能与组织反应相结合的评价案例。
The supplied index reports: HA and PDRN were covalently linked to form a hydrogel, which was assessed for viscoelasticity, hydration, degradation, injectability and biocompatibility, and compared with HA crosslinked hydrogel. In mouse experiments, volume maintenance beyond 24 weeks and changes in inflammatory and collagen-related findings were recorded.
Relevance to skincare research
The supplied index suggests: this study provides an evaluation case combining structure, properties and tissue response for skin-related biomaterials.
STUDY INFORMATION
研究信息
实验范围与结果
- 本索引由BTN整理，不是原始论文全文
- 报告的体积维持时间来自小鼠体内实验，并非人体临床数据
- 索引中未包含上市注射产品的注册或人体安全性证明
PUBLICATION & FULL TEXT
PDF 与出版来源
PUBLICATION METADATA · 出版信息
论文身份与引用信息。
- 原文题名
- An injectable hyaluronic acid-Polydeoxyribonucleotides (HA-PDRN) crosslinked hydrogel as a dermal filler
- 作者
- Guo jiahong · Fang wei · Wang feifei
- DOI
- 10.1016/j.eurpolymj.2024.113395
- ISSN
- 发表日期
- 2024-10-16
- 期刊
- European Polymer Journal
- 卷 / 期 / 文章号
- 219 / / 113395
- 出版社
- 关键词