茵陈提取物与UVB损伤：cGAS/STING通路研究

输入索引记载，该研究使用茵陈提取物预处理UVB照射的HaCaT角质形成细胞，检测细胞凋亡、DNA损伤、氧化应激和炎症介质释放，并分析cGAS/STING通路及相关成分。结果显示，提取物降低了细胞损伤和ROS水平，减少了IL-1α、IL-6与PGE2的释放，且通路检测提示cGAS/STING信号参与其中，绿原酸及其衍生物可能与相关靶点相互作用。

The supplied index reports a study in which Artemisia capillaris extract was used to pretreat UVB-exposed HaCaT keratinocytes, with measurements of apoptosis, DNA damage, oxidative stress and inflammatory mediator release, accompanied by analysis of the cGAS/STING pathway and related compounds. The results indicate that the extract reduced cellular damage and ROS levels, decreased the release of IL-1α, IL-6 and PGE2, and pathway assessments suggested involvement of cGAS/STING signalling, while chlorogenic acid and its derivatives may interact with relevant targets.